New RaDaR Cohort – MGRS

 

RaDaR is now open to a new Cohort of patients – Monoclonal Gammopathy of Renal Significance (MGRS) – which covers the following conditions:  

  • AH amyloidosis
  • AHL amyloidosis
  • AL amyloidosis
  • C3 glomerulonephritis with monoclonal gammopathy
  • Crystalglobulinaemia
  • Crystal-storing histiocytosis
  • Fibrillary Glomerulonephritis
  • Immunotactoid/Glomerulonephritis with Organised Microtubular Monoclonal Immunoglobulin Deposits (GOMMID)
  • Intracapillary monoclonal IgM without cryoglobulin
  • Intraglomerular/capillary lymphoma/leukaemia
  • Light chain cast nephropathy
  • Light chain proximal tubulopathy, crystalline
  • Light chain proximal tubulopathy, non crystalline
  • Monoclonal Immunoglobulin Deposition Disease (MIDD; includes Light Chain Deposition Disease – LCDD; Heavy Chair Deposition Disease – HCDD; and Light and Heavy Chain Deposition Disease – LHCDD)
  • Proliferative glomerulonephritis with monoclonal immunoglobulin deposits – PGNMID
  • Thrombotic Microangiopathy with monoclonal gammopathy
  • Type 1 cryoglobulinaemic Glomerulonephritis
  • Unclassified MGRS

No new approvals are needed to start recruiting these patients.

A Crib Sheet of details of the conditions that are included in the MGRS cohort is available to download from https://tinyurl.com/mgrs-crib-sheet or from request via Melanie.Dillon@renalregistry.nhs.uk